รศ.ดร.โสรัจสิริ เจริญสุดใจ 


Assoc. Prof. Dr.Sorujsiri Chareonsudjai
sorujsr@kku.ac.th​

Education


      • University of Manchester, Manchester, United Kingdom, Ph.D. (Microbiology) 2000
      • Mahidol University, Bangkok, Thailand, M.Sc. (Microbiology) 1989
      • Mahidol University, Bangkok, Thailand, B.Sc.(Biotechnology) 1986


Research Interest


      • Bacterial biofilms associated with pathogenesis
      • Burkholderia pseudomallei biofilms
      • Development chitosan and chitosan nanoparticles as antimicrobial agents and antibiofilms


Publication


  • Tun WST, Hongsing N, Sirithongsuk P, Nasompak S, Daduang S, Klaynongsruang S, et al. The synergistic action of silver nanoparticles and ceftazidime against antibiotic-resistant Burkholderia pseudomallei: A modifying treatment. Process Biochem. 2024;136:351-61.
         
  • Watakulsin K, Chuenchom C, Thapphan C, Thai TD, Chareonsudjai S, Faksri K, et al. Neutrophils form extracellular traps in response to Opisthorchis viverrini crude antigens, which are elevated in neutrophils from opisthorchiasis patients with hepatobiliary abnormalities. Biol Open. 2023;12(8).
         
  • Pakkulnan R, Thonglao N, Chareonsudjai S. DNase I and chitosan enhance efficacy of ceftazidime to eradicate Burkholderia pseudomallei biofilm cells. Scientific Reports. 2023;13(1):1059.
         
  • Nithimongkolchai N, Hinwan Y, Kaewseekhao B, Chareonsudjai P, Reungsang P, Kraiklang R, et al. MALDI-TOF MS analysis of Burkholderia pseudomallei and closely related species isolated from soils and water in Khon Kaen, Thailand. Infect Genet Evol. 2023;116:105532.
         
  • Meethai C, Vanaporn M, Intarak N, Lerdsittikul V, Withatanung P, Janesomboon S, et al. Analysis of the role of the QseBC two-component sensory system in epinephrine-induced motility and intracellular replication of Burkholderia pseudomallei. PLoS One. 2023;18(2):e0282098.
         
  • Mattrasongkram P, Wongkaewkhiaw S, Taweechaisupapong S, Chareonsudjai S, Techawiwattanaboon T, Ngamsiri T, et al. Vitamin D (1alpha,25(OH)2D3) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells. PLoS One. 2023;18(2):e0280944.
         
  • Hatrongjit R, Boueroy P, Jenjaroenpun P, Wongsurawat T, Meekhanon N, Chopjitt P, et al. Genomic characterization and virulence of Streptococcus suis serotype 4 clonal complex 94 recovered from human and swine samples. PLoS One. 2023;18(7):e0288840.
         
  • Bunma C, Noinarin P, Phetcharaburanin J, Chareonsudjai S. Burkholderia pseudomallei biofilm resists Acanthamoeba sp. grazing and produces 8-O-4′-diferulic acid, a superoxide scavenging metabolite after passage through the amoeba. Sci Rep. 2023;13(1):16578.
         
  • Thonglao N, Pakkulnan R, Paluka J, Chareonsudjai P, Kanokmedhakul S, Kanokmedhakul K, et al. Chitosan biological molecule improves bactericidal competence of ceftazidime against Burkholderia pseudomallei biofilms. Int J Biol Macromol. 2022;201:676-85.
         
  • Phoksawat W, Nithichanon A, Lerdsamran H, Wongratanacheewin S, Meesing A, Pipattanaboon C, et al. Phenotypic and functional changes of T cell subsets after CoronaVac vaccination. Vaccine. 2022;40(48):6963-70.
         
  • Khamwong M, Phanthanawiboon S, Salao K, Chareonsudjai S. Burkholderia pseudomallei biofilm phenotypes confined but surviving in neutrophil extracellular traps of varying appearance. Frontiers in Immunology. 2022;13:926788.
         
  • Anutrakunchai C, Wongkaewkhiaw S, Kanthawong S, Chareonsudjai S, Pakkulnan R, Taweechaisupapong S. Combination effects of DNase I and tobramycin on survival and biofilm architectures of Pseudomonas aeruginosa and Klebsiella pneumoniae isolated from chronic rhinosinusitis patients. Songklanakarin Journal of Science and Technology. 2022;44(5): 1306 – 13.
         
  • Muangsombut V, Withatanung P, Chantratita N, Chareonsudjai S, Lim J, Galyov EE, et al. Rapid Clinical Screening of Burkholderia pseudomallei Colonies by a Bacteriophage Tail Fiber-Based Latex Agglutination Assay. Appl Environ Microbiol. 2021;87(12):e0301920.
         
  • Wongkaewkhiaw S, Taweechaisupapong S, Thanaviratananich S, Bolscher JGM, Nazmi K, Anutrakunchai C, et al. D-LL-31 enhances biofilm-eradicating effect of currently used antibiotics for chronic rhinosinusitis and its immunomodulatory activity on human lung epithelial cells. PLoS One. 2020;15(12):e0243315.
         
  • Boueroy P, Boonmars T, Kanokmedhakul S, Chareonsudjai S, Lekphrom R, Srichangwang S. Promising Anticancer Effect of Aurisin A Against the Human Lung Cancer A549 Cell Line. Asian Pacific Journal of Cancer Prevention. 2020;21(1):49-54.
         
  • Pakkulnan R, Anutrakunchai C, Kanthawong S, Taweechaisupapong S, Chareonsudjai P, Chareonsudjai S. Extracellular DNA facilitates bacterial adhesion during Burkholderia pseudomallei biofilm formation. PLoS One. 2019;14(3):e0213288.